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13 de nov. de 2003 · We conducted the Valsartan in Acute Myocardial Infarction (VALIANT) trial to test the hypothesis that treatment with valsartan, an angiotensin-receptor blocker, alone or in combination with...
Background: The VALsartan In Acute myocardial iNfarcTion (VALIANT) trial compared outcomes with: (1) angiotensin-converting enzyme inhibition (ACEI) with the reference agent captopril; (2) angiotensin-receptor blockade (ARB) with valsartan; or (3) both in patients with heart failure (HF) and/or left ventricular systolic dysfunction (LVSD) after ...
23 de jun. de 2005 · VALIANT was a randomized, controlled trial of treatment with valsartan, captopril, or both in 14,703 patients with a first or subsequent acute myocardial infarction complicated by heart...
27 de sept. de 2018 · In the Valsartan in Acute Myocardial Infarction (VALIANT) trial, only half the patients with sudden death who underwent autopsy were found to have died from arrhythmic death. 34 In a...
Methods: Valsartan in Acute Myocardial Infarction (VALIANT) is a multicenter, double-blind, randomized, active controlled parallel group study comparing the efficacy and safety of long-term treatment with valsartan, captopril, and their combination in high-risk patients after MI.
13 de nov. de 2003 · Conclusions: Valsartan is as effective as captopril in patients who are at high risk for cardiovascular events after myocardial infarction. Combining valsartan with captopril increased the rate of adverse events without improving survival. Copyright 2003 Massachusetts Medical Society.
11 de ago. de 2003 · The VALsartan In Acute myocardial iNfarcTion (VALIANT) trial was designed to determine the relative effects of valsartan, an ARB; captopril, a proven ACEI; and their combination on mortality in patients with acute MI complicated by HF and/or LVSD.
