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The mycobacterial bacillus is encompassed by a remarkably elaborate cell wall structure. The mycolyl-arabinogalactan-peptidoglycan (mAGP) complex is essential for the viability of Mycobacterium tuberculosis and maintains a robust basal structure supporting the upper “myco-membrane.”
The pathogen Mycobacterium tuberculosis (Mtb), causing tuberculosis disease, features an extraordinary thick cell envelope, rich in Mtb-specific lipids, glycolipids, and glycans. These cell wall components are often directly involved in host–pathogen interaction and recognition, intracellular survival, and virulence.
7 de jul. de 2019 · Stokes RW, Norris-Jones R, Brooks DE, Beveridge TJ, Doxsee D and Thorson LM (2004) The glycan-rich outer layer of the cell wall of Mycobacterium tuberculosis acts as an antiphagocytic capsule limiting the association of the bacterium with macrophages.
17 de may. de 2023 · The cell wall of Mycobacterium is a complex structure associated with intrinsic resistance to clearance in infected cells with the lipid barrier functioning as a shield in harsh environments . The composition of the cell wall and hydrophobicity confer low permeability .
9 de oct. de 2017 · The plasma membranes (PM) and the native MM-containing cell walls (MMCW) of two rapid-growing mycobacterial species, Mycobacterium aurum and M. smegmatis, were isolated from their cell...
25 de abr. de 2023 · The cell wall of Mycobacterium is a complex structure associated with intrinsic resistance to clearance in infected cells with the lipid barrier functioning as a shield in harsh environments . The composition of the cell wall and hydrophobicity confer low permeability ( 20 ).
10 de jun. de 2019 · Mycobacterium tuberculosis has a unique cell envelope structure and composition, containing a peptidoglycan layer that is essential for maintaining cellular integrity and for virulence.
