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18 de ene. de 2018 · During sterilization, gamma rays efficiently eliminate microorganisms from the medical devices and tissue allografts, but also significantly change molecular structure of irradiated products, particularly fragile biologics such as cytokines, chemokines and growth factors.
More than 40 per cent of all single-use medical devices produced worldwide are sterilized with gamma irradiation. The IAEA helps its Member States set up radiation facilities and provides guidelines for the use of sterilization applications that use radiation.
18 de mar. de 2021 · Medical equipment, devices, and drugs are most commonly sterilized using gamma (γ)-irradiation. The main advantage of γ-irradiation is its high level of penetration and isothermal characteristics, which can appropriately manage heat-sensitive materials include inorganic metal oxides, polymer blends, or liquid crystals.
Gamma irradiation is capable of killing microorganisms by breaking their chemical bonds, producing free radicals that attack the nucleic acid of the microorganism. Sterility by gamma irradiation is achieved mainly by the alteration of nucleic acid and preventing the cellular division.
27 de feb. de 2018 · Gamma-ray irradiation at doses of ≥15 kGy was required for effective sterilization as evidenced by complete eradication of gram positive and negative bacteria. γ-PPy substrates also showed...
15 de sept. de 2020 · Gamma (γ) radiation is widely used to sterilize materials in a variety of settings. It is used in the food [ 1 ], pharmaceutical [ 2] and medical industries [ 3, 4] due to the ability of γ-radiation to inactivate pathogens through nucleic acid damage, whilst leaving proteins and other structures largely intact.
18 de ene. de 2018 · During sterilization, gamma rays efficiently eliminate microorganisms from the medical devices and tissue allografts, but also significantly change molecular structure of irradiated products, particularly fragile biologics such as cytokines, chemokines and growth factors.
