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  1. Screening for Frailty in the Clinical Setting. Frailty is associated with greater prevalence of adverse health outcomes, including mortality, disability, worsening mobility, falls, and hospitalization in the US population 4, and is predictive of these outcomes in epidemiological cohorts 11,20.

  2. 16 de oct. de 2023 · Nature Aging - Cognitive frailty (CF) is the complex and intertwined co-occurrence of physical frailty and cognitive decline. Untangling the interplay between these two domains and...

  3. In addition, for older adults with cognitive frailty, an effective flow diagram from primary screening through comprehensive assessment to multidimensional intervention needs to be developed for future implementation in both clinical and community settings.

  4. 1 de mar. de 2019 · Screening instruments have often been used to determine objective cognitive decline. •. Lifespan trajectories should be taken into account in understanding cognitive frailty. •. A strong operational definition of cognitive frailty is necessary. •. Interventional studies are needed to establish the role of preventive strategies. Abstract. Objective.

  5. 7 de mar. de 2019 · The emerging biomarkers of sarcopenia, physical frailty, and cognitive impairment will provide the basis to establish more reliable clinical and research criteria for cognitive frailty, using different operational definitions for frailty and cognitive impairment and useful clinical, biological, and imaging markers for this novel ...

  6. 4 de mar. de 2017 · Davide Seripa, Francesco Panza & Zhuowei Yu. 3069 Accesses. 35 Citations. 2 Altmetric. Explore all metrics. Abstract. Physical frailty and cognitive frailty are two important targets of secondary intervention in aging research to narrow the gap between life and health span.

  7. Early screening leads to better prevention and management of frailty, increasing the possibility of reversing it. Developing assessment tools by incorporating disease states of older adults using effective interventions has become the most effective approach for preventing and controlling frailty.