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20 de may. de 2020 · The replication of the viral genome within the infected cells is a key stage of the SARS-CoV-2 life cycle. It is a complex process involving the action of several viral and host proteins in order to perform RNA polymerization, proofreading and final capping.
- Structure of replicating SARS-CoV-2 polymerase - PubMed
The new coronavirus severe acute respiratory syndrome...
- Insights into SARS-CoV-2 genome, structure, evolution, pathogenesis and ...
Abstract. The sudden emergence of severe respiratory...
- Coronaviruses: An Updated Overview of Their Replication and ...
The replicase gene constitutes two ORFs, rep 1a and rep 1b,...
- Structure of replicating SARS-CoV-2 polymerase - PubMed
25 de nov. de 2021 · Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other coronaviruses rely on a cohort of specialized viral proteins to transcribe and replicate their RNA genomes.
1 de feb. de 2023 · The SARS-CoV-2 RNA-dependent RNA polymerase coordinates viral RNA synthesis as part of an assembly known as the replication–transcription complex (RTC) 1. Accordingly, the RTC is...
21 de may. de 2020 · Nature - A cryo-electron microscopy structure of the RNA-dependent RNA polymerase of SARS-CoV-2 sheds light on coronavirus replication and enables the analysis of the...
