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Organization and Function of Mitochondria. Mitochondria are surrounded by a double-membrane system, consisting of inner and outer mitochondrial membranes separated by an intermembrane space (Figure 10.1). The inner membrane forms numerous folds (cristae), which extend into the interior (or matrix) of the organelle.
18 de feb. de 2020 · Here, we discuss mitochondrial membrane dynamics and their regulation and describe how bioenergetics and cellular signalling are linked to these dynamic changes of mitochondrial morphology.
29 de oct. de 2015 · The inner and outer membranes of mitochondria define three compartments within the organelle, each with its distinct role and corresponding protein components. The innermost compartment, surrounded by the inner membrane, is the mitochondrial matrix.
Hace 2 días · mitochondrion, membrane-bound organelle found in the cytoplasm of almost all eukaryotic cells (cells with clearly defined nuclei), the primary function of which is to generate large quantities of energy in the form of adenosine triphosphate (ATP).
Mitochondria in healthy cells generate an electrochemical potential that serves in oxidative phosphorylation and drives the import of proteins into the organelle. Damage that leads to a loss (blue) of mitochondrial membrane potential can lead to a loss of protein import efficiency.
23 de ene. de 2024 · Integral membrane proteins called porins allow for transport between the mitochondrion and the cell’s cytosol. Inner Membrane: The inner membrane is highly convoluted, forming folds known as cristae. This membrane contains proteins involved in the electron transport chain and ATP synthesis.
The maintenance of the phospholipid composition in the mitochondrial membranes is essential for mitochondrial function, structure, and biogenesis and relies on the metabolism of phospholipids, transport into mitochondria, and supply of lipids from the diet.
