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  1. 15 de may. de 2024 · Here, we identify the S. aureus lipase Lip2 as a novel resistance factor against AFAs. Lip2 detoxifies AFAs via esterification with cholesterol.

  2. Hace 2 días · Liu, X., Viswanadhapalli, S., Kumar, S. et al. Author Correction: Targeting LIPA independent of its lipase activity is a therapeutic strategy in solid tumors via induction of endoplasmic reticulum ...

  3. Hace 16 horas · Lipase activity is also highly bile salt dependent, [50, 51] and thus the lipase-responsive macromolecular sensors were the least robust among the three. However, since the drain bags are often attached to patients for multiple days, a lipase responsive sensing element can serve as a long-term monitoring sensor and can be indicative of large leaks.

  4. Hace 6 días · Enzymatic catalysts, such as lipases, have been extensively studied due to their promise as an alternative to chemical catalysts. They offer advantages like biodegradability (green biotechnology) and the potential for enzyme recycling (turnover), leading to reduced operational costs. The primary objective of this study was to produce lipase from the fungus Penicillium polonicum through solid ...

  5. Hace 16 horas · Lipases, crucial catalysts in biochemical synthesis, find extensive applications across industries such as food, medicine, and cosmetics. The efficiency of lipase-catalyzed reactions is significantly influenced by the choice of solvents. Polar organic solvents often result in a decrease, or even loss, of lipase activity. Conversely, nonpolar organic solvents induce excessive rigidity in ...

  6. 14 de may. de 2024 · Therefore, designing lipase-responsive strategies for biofilm diagnosis and treatment is urgent and necessary for biofilm detection in a clinical setting. Herein, a multifunctional theranostic nanoplatform has been fabricated to facilitate real-time detection of wound infection and photothermal-triggered CIP release for biofilm ...

  7. 30 de abr. de 2024 · Altering lipase activity can either lead to therapeutic benefits or cause disease and can also improve the applicability of these enzymes as biocatalysts. Modulators of lipases include activators and inhibitors, either obtained from natural sources or synthesized.

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