Resultado de búsqueda
26 de may. de 2022 · Este fármaco se centra en el uso de la gacyclidina, que bloquea uno de los receptores de glutamato del cerebro, concretamente el NMDA. Se ha demostrado que el glutamato provoca hiperactividad en los receptores auditivos, de forma que el OTO 313 calmaría esta actividad, bloqueando el receptor.
4 de mar. de 2018 · El OTO-311 se basa principalmente en la gacyclidina, una potente droga que actúa en el receptor NMDA (uno de los 3 tipos de glutamato en nuestro cerebro) para reducir la hiperactividad de los nervios auditivos y poder combatir el pitido en los oídos.
La colchicina es un medicamento muy utilizado para prevenir las crisis agudas de gota y tratar la gota crónica, ya que disminuye la deposición de cristales de urato y la consecuente respuesta inflamatoria, reduciendo así el dolor.
Gacyclidine, a potent and specific phencyclidine analogue noncompetitive N -methyl D -aspartate receptor antagonist, was previously shown to provide neuroprotection through improvement of the functional, histologic, and electrophysiologic status of the injured rat spinal cord following experimental contusion with an absence of dose-related adver...
21 de oct. de 2016 · It is scheduled to be annotated soon. Generic Name. Gacyclidine. DrugBank Accession Number. DB13096. Background. Gacyclidine has been used in trials studying the treatment of Tinnitus. Type. Small Molecule.
Gacyclidine administration was associated with a significantly smaller region of cord damage at the lesion core and proximal to the lesion. The degree of cord damage was significantly reduced in the 1 mg/kg cohort compared to higher doses of 2.5 mg/kg and 5 mg/kg.
Gacyclidine is a psychoactive drug that was used for helping with body trauma in humans. While seeing most tests on animals, it was never used commercially to the degree as other painkillers or psychoactive drugs.
