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  1. 3 de nov. de 2023 · The epicardium is the outermost layer of the heart. It is actually the visceral layer of the serous pericardium, which adheres to the myocardium of the heart. Histologically, it is made of mesothelial cells, the same as the parietal pericardium.

  2. 27 de jun. de 2018 · Epicardial nuclei are labelled in violet (tcf21:nucEGFP), and phosphorylated myosin light chain 2 (pMLC) at Ser19, an indicator of mechanical tension, is labelled in cyan. Scale bar: 100 μm....

  3. Epicardium during cardiac development. EPDCs (Epicardium-derived progenitor cells) emerge from the fetal epicardium through the process of epithelial-to-mesenchymal transition (EMT) and contribute to various cardiac lineages, such as cardiac fibroblasts (CFs), smooth muscle cells (SMCs), and pericytes (PCs).

  4. 12 de may. de 2022 · To study the potency of the post-metamorphic salamander epicardium, we developed a lineage tracing strategy that selectively labels the epicardium in an unbiased genetic marker-independent manner.

  5. 23 de sept. de 2021 · The epicardium is an essential cell population during cardiac development. It contributes different cell types to the developing heart through epithelial-to-mesenchymal transition (EMT) and it secretes paracrine factors that support cardiac tissue formation.

  6. Abstract. The epicardium, the outermost tissue layer that envelops all vertebrate hearts, plays a crucial role in cardiac development and regeneration and has been implicated in potential strategies for cardiac repair.

  7. 28 de mar. de 2018 · The disruption of C/EBP signalling in the adult epicardium reduces injury-induced neutrophil infiltration and improves cardiac function, revealing a previously unappreciated role for the epicardium in regulating the inflammatory response after injury.