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Learn how DNA replication is semiconservative and how DNA polymerases, primase, helicase, and other enzymes work together to copy DNA in E. coli. Explore the roles of leading and lagging strands, Okazaki fragments, and origins of replication.
In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule. DNA replication occurs in all living organisms acting as the most essential part of biological inheritance .
When a cell divides, it is important that each daughter cell receives an identical copy of the DNA. This is accomplished by the process of DNA replication. The replication of DNA occurs during the synthesis phase, or S phase, of the cell cycle, before the cell enters mitosis or meiosis.
Learn how cells make near-perfect copies of DNA using a template strand as a guide. Explore the four major stages of DNA replication: initiation, unwinding, primer synthesis, and elongation. Discover the role of DNA polymerases and other enzymes in the process of DNA replication.
DNA Replication Mechanisms. All organisms must duplicate their DNA with extraordinary accuracy before each cell division. In this section, we explore how an elaborate “replication machine” achieves this accuracy, while duplicating DNA at rates as high as 1000 nucleotides per second. Go to: Base-Pairing Underlies DNA Replication and DNA Repair.
