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1976 PhD, University College of London. An internationally recognized cancer expert, Dr. Lane is most notable for his contributions to the discovery of the p53 tumor suppressor protein, named by him as "the guardian of the genome" and implicated in over 50 percent of all human cancers.
Sir David Philip Lane FRCP FRCSE FMedSci FRS FRSE (born 1 July 1952) is a British immunologist, molecular biologist and cancer researcher. He is currently working in the Department of Microbiology, Tumor and Cell Biology at the Karolinska Institute and is Chairman of Chugai Pharmabody.
Professor Sir David Lane. Photo: Ulf Sirborn The protein p53 , widely known as the guardian of the genome, was discovered by Prof. Sir David Lane in 1979 and has over the years been recognized as a tumor suppressor gene mutated in more than half of all malignant tumors occurring in adults.
David P Lane. A*STAR. Verified email at p53lab.a-star.edu.sg. Articles Cited by Public access. Title. Sort. Sort by citations Sort by year Sort by title. Cited by. ... DP Lane, RT Hay. The EMBO journal, 1999. 837: 1999: Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines. J Bartek, R Iggo, J Gannon, DP Lane ...
12 de dic. de 2013 · Abstract. DNA manipulation routinely requires competent bacteria that can be made using one of numerous methods. To determine the best methods, we compared four commonly used chemical methods (DMSO, MgCl2-CaCl2, CaCl2 and Hanahan's methods) on frequently used Escherichia coli (E. coli) strains: DH5α, XL-1 Blue, SCS110, JM109, TOP10 ...
Professor Sir David Lane made the landmark discovery of the p53 cancer gene in 1979. He is currently the Chief Scientist of the Agency for Science, Technology and Research (A*STAR) in Singapore, where his main role is to advise and engage in scientific development across the Biomedical Research Council (BMRC) and the Science and Engineering ...
Frontiers in Basic Cancer Research 2011: Interview with Sir David P. Lane, Ph.D., chief scientist, Agency for Science, Technology and Research, SingaporeDr. ...
