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22 de abr. de 2024 · Notably, few studies have focused on exploring inflammatory markers in both physical frailty and cognitive impairment, posing a major challenge in elucidating the link between them. Therefore, substantial efforts are required for the better prevention of physical frailty and cognitive impairment.
2 de may. de 2024 · Our latest research showed an association between frailty and abnormal mechanical properties of the CNS, thereby implying a major role of the CNS in this context (Vallet et al., 2020). Cognitive impairment has emerged as a major contributing factor to susceptibility to adverse outcomes, as supported by Cesari et al. .
17 de abr. de 2024 · Frailty is commonly defined as a state of extreme vulnerability to external and internal stressors that increases the risk of adverse health outcomes 5 6, including falls, physical limitations, cognitive disorders, hospitalisation and mortality.7–9 According to a meta- analysis conducted by O’Caoimh et al,10 the prevalence of frailty among older...
26 de abr. de 2024 · Cognitive frailty, as an important subtype of frailty, is a syndrome characterised by cognitive dysfunction caused by physiological factors, excluding Alzheimer's disease and other types of dementia. It is characterised by the coexistence of physical frailty and cognitive impairment.
26 de abr. de 2024 · Sarcopenia, frailty, and cognitive function, including Mini-Mental State Examination (MMSE) scores, were evaluated. The patients’ mean age was 79.2 ± 6.3 years (male, 34.9%). PP and mean blood...
18 de abr. de 2024 · Introduction. Alzheimer’s disease (AD) and frailty are two profound health concerns that exert a substantial impact on the aging population. AD is characterized by a relentless neurodegenerative process resulting in cognitive deterioration, memory loss, and alterations in behavior and physical capabilities.
23 de abr. de 2024 · Conceptually, frailty is a “state” of health that reflects reduced physiologic complexity, impaired energetics, decreased physiologic reserve and a diminished ability to maintain or regain physiologic homeostasis [ 2 •].
