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1. cdn.who.int › media › docsGuidelines and Principles for Safe Blood Transfusion Practice

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   through blood transfusion is more than 90% efficient. Preventing the spread of HIV through blood and blood products is, however, a goal that can be attained by every national blood programme. In developing countries, blood transfusion services have traditionally ... The Blood Cold Chain Blood Collection

2. ashpublications.org › blood › articleCold Agglutinin Disease Transfusion Practices in the United...

   ashpublications.org › blood › article

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   13 de nov. de 2019 · Cold agglutinin disease (CAD) is a rare autoimmune hemolytic anemia (AIHA) accounting for 20% of all cases, with no approved therapies and limited management options for patients. CAD is characterized by immunoglobulin M-mediated erythrocyte agglutination, which triggers activation of the classical complement pathway leading to ...

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4. ashpublications.org › blood › articleCold agglutinin disease | Blood | American Society of Hematology

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   15 de ago. de 2013 · The thermal amplitude of the cold agglutinin antibody in many patients is such that physiologic peripheral cooling results in antibody binding sufficient to cause anemia. 52 Supportive transfusions may be used in patients with severe anemia.

5. www.uptodate.com › contents › cold-agglutinin-diseaseCold agglutinin disease - UpToDate

   www.uptodate.com › contents › cold-agglutinin-disease

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   1 de abr. de 2024 · Cold agglutinin disease (CAD) is a form of autoimmune hemolytic anemia (AIHA) in which cold agglutinins (IgM autoantibodies against red blood cell [RBC] antigens that bind at cold temperatures) can cause clinical symptoms related to RBC agglutination in cooler parts of the body and hemolytic anemia. This topic reviews the ...

6. ashpublications.org › blood › articleHow I treat cold agglutinin disease | Blood | American Society of...

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   11 de mar. de 2021 · How I Treat, Immunobiology and Immunotherapy, Red Cells, Iron, and Erythropoiesis. Topics: anemia, bendamustine, b-lymphocytes, cold hemagglutinin disease, complement system proteins, hemolysis, rituximab, adrenal corticosteroids, glucocorticoids, mineralocorticoids.

7. www.ncbi.nlm.nih.gov › pmc › articlesCold Agglutinin Disease - PMC - National Center for Biotechnology...

   www.ncbi.nlm.nih.gov › pmc › articles

   17 de jul. de 2020 · Symptomatic anemia can be treated with RBC transfusion. Blood bank testing for underlying alloantibodies and crossmatch testing should be performed at 37°C . It is important to note, though, that cold agglutinins can cause interference with laboratory testing, such as ABO blood typing results and hematocrit levels in a CBC .

8. www.hematologyandoncology.net › archives › june-2019How I Treat Cold Agglutinin Hemolytic Anemia

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   How I Treat Cold Agglutinin Hemolytic Anemia. Morie A. Gertz, MD, MACP. Roland Seidler Jr Professor of the Art of Medicine Consultant Hematologist Mayo Clinic Rochester, Minnesota. Download PDF. Overview. • Cold agglutinin disease is an immune-mediated hemolytic anemia characterized by complement on the red cell surface.