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24 de abr. de 2024 · DOI: 10.1016/j.cell.2024.03.027 Abstract Cysteine-focused chemical proteomic platforms have accelerated the clinical development of covalent inhibitors for a wide range of targets in cancer.
Hace 4 días · DOI: 10.1038/s41375-024-02276-w Corpus ID: 269740077; TIF1β activates leukemic transcriptional program in HSCs and promotes BCR::ABL1-induced myeloid leukemia. @article{Morii2024TIF1AL, title={TIF1$\beta$ activates leukemic transcriptional program in HSCs and promotes BCR::ABL1-induced myeloid leukemia.}, author={Mariko Morii and Sho Kubota and Mihoko Iimori and Takako Yokomizo-Nakano and Ai ...
Hace 6 días · Direct observation of a condensate effect on super-enhancer controlled gene bursting. Manyu Du, Simon Hendrik Stitzinger, Jan-Hendrik Spille, Won-Ki Cho, ... Ibrahim I. Cissé. Pages 2595-2598. View PDF. Read the latest articles of Cell at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature.
23 de abr. de 2024 · MARIKO NAITO (Graduate School of Biomedical and Health Sciences (Dentistry & Oral Health Sciences)) Last Updated :2024/04/23. Affiliations, Positions. Graduate School of Biomedical and Health Sciences (Dentistry & Oral Health Sciences), Professor. Web Site. https://oral-epi.jpn.org/?lang=en. E-mail. naitom hiroshima-u.ac.jp. Self-introduction.
Hace 2 días · Background: Chemotherapy is a common treatment for pediatric cancer. Although life prognosis is improving because of advances in medical science, it is important to deal with late effects such as dental abnormalities. We investigated the association between dental abnormalities and chemotherapy by age and tooth type. Methods: Among the 568 patients referred to the pediatric dentistry ...
8 de may. de 2024 · There is an urgent need to maximize the effectiveness of existing malaria interventions and optimize the deployment of novel countermeasures. When assessing the effects of interventions against malaria, it is imperative to consider the interdependence of people and the resulting indirect effects, without which the impact on health outcomes and their cost-effectiveness may be miscalculated.
Hace 1 día · Cell-cycle entry and subsequent G1 to S phase transition are crucial for mammalian cell proliferation. The pathway mediated by members of the ErbB receptor family (ErbB1/2/3/4) plays an important role in the proliferation of several types of human cancer cells, and increased ErbB2/HER2 activity is often observed in malignant breast cancer. However, the underlying mechanisms, such as the ...
