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In toxicology, the median lethal dose, LD 50 (abbreviation for "lethal dose, 50%"), LC 50 (lethal concentration, 50%) or LCt 50 is a toxic unit that measures the lethal dose of a given substance. The value of LD 50 for a substance is the dose required to kill half the members of a tested population after a specified test duration.
Se define como la cantidad de una sustancia que, cuando se administra a un grupo de animales de prueba, causa la muerte del 50% de ellos dentro de un período de tiempo determinado, generalmente 24 horas. La LD50 se expresa en miligramos de sustancia por kilogramo de peso corporal (mg/kg).
9 de mar. de 2021 · Lethal dose (LD) The dose of radiation expected to cause death to 50 percent of an exposed population within 30 days (LD 50/30). Typically, the LD 50/30 is in the range from 400 to 450 rem (4 to 5 sieverts) received over a very short period.
The median lethal dose, LD 50 (abbreviation for "lethal dose, 50%"), LC 50 (lethal concentration, 50%) or LCt 50 (lethal concentration and time) of a toxin, radiation, or pathogen is the dose required to kill half the members of a tested population after a specified test duration.
31 de ago. de 2022 · El LD de LD50 es de origen anglosajón y proviene del término en inglés para dosis letal que es lethal dose, mientras que el 50 proviene del 50% de la población de un organismo específico que, en promedio, morirá al ser expuesto a la dosis de la sustancia en cuestión.
Hace 5 días · LD stands for "Lethal Dose". LD 50 is the amount of a material, given all at once, which causes the death of 50% (one half) of a group of test animals. The LD 50 is one way to measure the short-term poisoning potential (acute toxicity) of a material. Toxicologists can use many kinds of animals but most often testing is done with rats ...
The LD 50 is the dose that kills half (50%) of the animals tested (LD = "lethal dose"). It is a standardized measure for expressing and comparing the toxicity of chemicals. LD 50 values are given for common drugs (e.g. ibuprofen and aspirin), common household ingredients including water, table sugar (sucrose), salt (sodium chloride ...
