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Background Changes in the cerebral hemispheric white matter are detected with increasing frequency by CT and MRI among persons older than 60 years. The pathogenesis, clinical significance, and morphological substrate of these changes are incompletely understood.
Lesions of the cerebral white matter (WM) result in focal neurobehavioral syndromes, neuropsychiatric phenomena, and dementia. The cerebral WM contains fiber pathways that convey axons linking cerebral cortical areas with each other and with subcortical structures, facilitating the distributed neural circuits that subserve sensorimotor function ...
These MRI studies suggest that visible WMHs are “only the tip of the iceberg” and that the underlying pathophysiology is a diffuse process affecting small blood vessels in much of the white matter and other parts of the brain.
Each cerebral hemisphere has an outer layer of cerebral cortex which is of grey matter and in the interior of the cerebral hemispheres is an inner layer or core of white matter known as the centrum semiovale.
14 de dic. de 2019 · White matter tracts in the brain, also known as white matter fibers, are classified into three categories: projection fibers; association fibers; commissural fibers; The white matter can be observed well on T1W, T2W and FLAIR sequences.
Diffuse ischemic white matter disease impairs executive functioning, information processing speed, and gait. Neuroimaging techniques, such as tissue segmentation, Diffusion Tensor Imaging, MR Spectroscopy, functional MRI and amyloid PET, probe microstructural integrity, molecular biology, and activation patterns, providing new insights into ...
18 de jul. de 2021 · White fibers of the brain are classified into three types: (1) association fibers that interconnect different cortical areas in the same hemisphere, (2) commissural fibers that connect similar regions of the two hemispheres across the midline, and (3) projection fibers that connect the cortex with subcortical regions, the brainstem ...
