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Overview. Editors: Pierre Hainaut, Klas G. Wiman. p53 is considered the most important cancer gene. p53 is a target for novel cancer therapy strategies already underway. p53 works as a sensor of oncogenic environmental stress. Written by world-leading scientists in the p53 field.
This book, written by world-leading p53 researchers including many of those who have shaped the field over the past 25 years, provides unique insights into the progress of the p53 field and the prospects for better cancer diagnosis and therapy the future.
Reference functional assays and structural analysis: Given the huge diversity of cellular and animal models for wild-type or mutant p53 functions, it will be important to set up standard,...
xi, 446 p. : 25 cm. Skip to main content. We will keep fighting for all libraries - stand with us! A line drawing of ... 25 years of p53 research. Publication date 2005 Topics p53 antioncogene Publisher Dordrecht : Springer ... Pierre; Wiman, Klas Boxid IA1806219 Camera Sony Alpha-A6300 (Control) Collection_set
18 de abr. de 2005 · p53 has emerged as a key tumor suppressor and important target for novel cancer therapy. This book, written by world-leading p53 researchers including many of those who have shaped the field over the past 25 years, provides unique insights into the progress of the field and the prospects for better cancer diagnosis and therapy in the ...
target wild-type or mutant p53. After 25 years of research, p53 has had a tremendous impact on our understanding of the molecular biology of cancer. As this knowledge develops to reveal more and more intricate pathways, the p53 protein will continue to be the « Ariadne thread » pointing out new routes in the maze of cancer biology.
1 de ene. de 2005 · 25 Years of p53 Research. January 2005. DOI: 10.1007/978-1-4020-2922-6. ISBN: 978-1-4020-2920-2. Authors: Pierre Hainaut. University of Grenoble. Klas G Wiman. Karolinska Institutet....
