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Levi Todd was an American pioneer, businessman and civil servant who co-founded Lexington, Kentucky and fought in the American Revolutionary War. He was also the grandfather of Mary Todd Lincoln, the wife of President Abraham Lincoln.
Articles 1–20. Assistant Professor, SUNY Upstate Medical University - Cited by 1,603 - Neuroscience - retina - glia - regeneration.
Dr. Todd received his PhD from The Ohio State University in 2017 and completed his postdoctoral work at The University of Washington in 2023. His expertise encompasses cellular and molecular neuroscience, neuroimmunology, and genomics.
Levi Todd is an assistant professor at the Center for Vision Research (CVR) who studies how to regenerate neurons in the eye and brain. He aims to reverse vision loss caused by diseases such as glaucoma and macular degeneration using developmental cues and glial cells.
In brief. Endogenous regeneration strategies hold great therapeutic promise for degenerative diseases of the nervous system. In this report, Todd et al. demonstrate that combinations of proneural transcription factors can stimulate M€uller glia to efficiently regenerate new neurons in the. in vivo. adult mouse retina. ll. Article.
Home > Investigators > Levi Todd, PhD. Research. Engineering Glia to Regenerate Neurons. We have developed strategies to stimulate regeneration of neurons in vivo in the adult mouse retina. This is done by overexpressing the proneural transcription factor Ascl1 in Muller glia.
19 de oct. de 2021 · Recently, we reported that overexpressing the transcription factor Ascl1 in Müller glia (MG) is sufficient to stimulate MG to regenerate functional neurons in the adult mouse retina. However, this process is inefficient, and only a third of the Ascl1-expressing MG generate new neurons.
