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  1. Quentin McAfeeProsser Lab. Ph.D. QMcAfee@pennmedicine.upenn.edu. Research interests: Cardiac mechanobiology, titin, and proteostasis. Hometown: Colorado Springs, CO. Education: B.S. in Biology, University of South Florida. Hobbies: Hiking, kayaking, or mountain biking to the most remote point on the map I can get to. PUBLICATIONS:

  2. 16 de ene. de 2024 · Truncated titin protein in dilated cardiomyopathy incorporates into the sarcomere and transmits force. J Clin Invest. 2024 Jan 16;134 (2):e170196. doi: 10.1172/JCI170196. Authors. Quentin McAfee 1 , Matthew A Caporizzo 2 , Keita Uchida 2 , Kenneth C Bedi Jr 1 , Kenneth B Margulies 1 , Zolt Arany 1 , Benjamin L Prosser 2. Affiliations.

  3. 3 de nov. de 2021 · Truncating variants in TTN (TTNtvs) are the most common known cause of nonischemic dilated cardiomyopathy (DCM), but how TTNtvs cause disease has remained controversial.

  4. Quentin McAfee's 21 research works with 1,805 citations and 2,536 reads, including: Truncated titin protein in dilated cardiomyopathy incorporates into the sarcomere and transmits force.

  5. 11 de nov. de 2021 · Here, using tissues from the hearts of patients with DCM and TTN-truncating variants as well as human induced pluripotent stem cells differentiated into cardiomyocytes, Fomin et al. and McAfee et al. identified both the presence of truncated titin proteins and less-abundant full-length titin protein.

  6. 1 de ene. de 2024 · Truncated titin protein in dilated cardiomyopathy incorporates into the sarcomere and transmits force. Quentin McAfee, 1 Matthew A. Caporizzo, 2 Keita Uchida, 2 Kenneth C. Bedi, Jr., 1 Kenneth B. Margulies, 1 Zolt Arany, 1 and Benjamin L. Prosser 2. Author information Article notes Copyright and License information PMC Disclaimer.

  7. 9 de nov. de 2023 · Truncated titin protein in dilated cardiomyopathy incorporates into the sarcomere and transmits force. Quentin McAfee, … , Zolt Arany, Benjamin L. Prosser. Published November 9, 2023.