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Herpes zoster is a localised, blistering and painful rash caused by reactivation of varicella-zoster virus (VZV). Herpes zoster is also called shingles. VZV is also called herpesvirus 3 and is a member of the Herpesvirales order of double-stranded DNA viruses. Herpes zoster. Herpes zoster.
Herpes simplex, varicella and herpes zoster infections show identical histology. Clinical correlation or immunohistochemistry and/or viral culture or PCR (of an appropriate swab or tissue specimen) is required to differentiate these viral infections. Histology of herpes infections. The histology of herpes infections is very distinctive.
Herpes zoster images. Authoritative facts about the skin from DermNet New Zealand.
The Tzanck smear is mainly used in an acute setting to rapidly detect a herpes infection or to distinguish Stevens- Johnson syndrome / toxic epidermal necrolysis (SJS/TEN) from staphylococcal scalded skin syndrome. However, it can be used to diagnose a variety cutaneous infections and blistering diseases.
Aciclovir is a synthetic compound with a similar molecular structure to purine nucleoside. It has been shown to stop the growth of herpes simplex virus (HSV), Varicella zoster virus (VZV) (the cause of chickenpox and shingles), Epstein-Barr virus (EBV, the cause of infectious mononucleosis), and to a lesser extent cytomegalovirus (CMV).
Ramsay Hunt syndrome is a rare peripheral facial neuropathy. It is a type of shingles due to reactivation of the varicella zoster virus (VZV) in the geniculate ganglion of cranial nerve VII, which supplies the facial nerve. Ramsay Hunt syndrome is characterised by unilateral facial weakness and painful blisters — either in the ear canal on ...
Herpes simplex is a common viral infection that presents with localised blistering. It affects most people on one or more occasions during their lives. Herpes simplex is commonly referred to as cold sores or fever blisters, as recurrences are often triggered by a febrile illness, such as a cold. Herpes labialis. Herpes simplex on the cheek.
Post-herpetic neuralgia is often used to describe any pain that persists after herpes zoster blisters have cleared up. Some experts prefer to reserve the term only for pain that lasts for more than 28 days or more than 120 days. 'Acute' and 'sub-acute' herpetic neuralgia may be used to describe earlier pain associated with herpes zoster infection.
Chickenpox is a highly contagious viral infection that causes an acute fever and blistered rash, mainly in children. Chickenpox is also known as varicella. The name may be derived from the French term for chickpea, chiche pois. Another theory is that the word 'chicken' was derived from a slang term for 'child'.
Clinical features. Herpes simplex virus (HSV) type 1 mainly affects the face and type 2 mainly affects genital skin, although in 10% of infections the reverse is true and any mucocutaneous site may be affected. The virus is inoculated into the affected area and is more likely with minor injury, e.g. facial lesions contracted in rugby (‘scrum ...
