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  1. Edited by the 1991 winners of the Nobel Prize in Physiology or Medicine, this Second Edition includes new chapters covering such applications as capacitance measurements; single-cell PCR measurements; whole-cell recording from brain slices in combination with imaging techniques; atomic force microscopy of cells and membranes attached to glass ...

  2. About this book. Single-channel recording has become a widely used tool for the study of ion permeation mechanisms in biological membranes. Whereas the technique might have been considered an "art" after its introduction in 1976, it developed into a relatively simple method after it became possible to obtain high-resistance (several gigaohm) ...

  3. 1 de nov. de 2007 · Electrophysiological recording of single-channel currents is the most direct method available for obtaining detailed and precise information about the kinetic behavior of ion channels.

  4. 20 de jul. de 2017 · Finally, single-channel activities can be recorded from endolysosomal membranes . Using specific solutions, single-channel events can be recorded in cells expressing TRPML1 channels.

  5. 20 de jun. de 2022 · Single-channel recording is a single-molecule technique that measures the activity of a single membrane channel, usually by means of a patch pipette.

  6. 11 de nov. de 2013 · Single-channel recording has become a widely used tool for the study of ion permeation mechanisms in biological membranes. Whereas the technique might have been considered an "art" after...

  7. 30 de oct. de 2020 · Single-channel recording. 1 Introduction. Electrophysiology is an essential tool to aid the study of the functions and dysfunctions of electrically excitable cells (typically neurons) and their networks and, increasingly, nonexcitable cells.