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  1. 28 de nov. de 2023 · The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches.

    • Nucleotide BLAST

      PSI-BLAST allows the user to build a PSSM (position-specific...

    • Needleman-Wunsch

      If there is no similarity, no alignment will be returned....

    • Protein BLAST

      PSI-BLAST allows the user to build a PSSM (position-specific...

    • Overview

      What is BLAST? The Basic Local Alignment Search Tool (BLAST)...

    • NCBI Bookshelf

      This manual documents the BLAST (Basic Local Alignment...

  2. BLAST is a computer algorithm that is available for use online at the National Center for Biotechnology Information (NCBI) website, as well as many other sites. BLAST can rapidly align and...

  3. The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between protein or nucleotide sequences. The program compares nucleotide or protein sequences to sequence in a database and calculates the statistical significance of the matches.

  4. In bioinformatics, BLAST (basic local alignment search tool) is an algorithm and program for comparing primary biological sequence information, such as the amino-acid sequences of proteins or the nucleotides of DNA and/or RNA sequences.

  5. Sequence alignment is the process of arranging the characters of a pair of sequences such that the number of matched characters is maximized. We can describe the alignment between two sequences with the following notation: GCGTAACACGTGCG-- | ||| ||||||. AC--AACCCGTGCGAC. The vertical bars "|" "|", or pipes, represent matching characters.