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24 de abr. de 2023 · Carbon dioxide, urea, uric acid, and creatinine are disposed into the maternal blood from the fetal circulation. Maternal blood contains IgG antibodies which diffuse through the placenta and provide naturally acquired passive immunity to the infant during the crucial first few months of life.
Placental cells (trophoblasts) invade both into the tissue of the uterus and into the maternal blood vessels nearest to the site of implantation (the spiral arteries (SAs)) and transform these allowing a relatively high and steady flow of nutrient-rich blood to perfuse the placenta.
Maternal blood is an ideal system for studying methylation changes and development of disease biomarkers, whereas fetal origin tissues like cord blood, cord tissue and placenta are good sources to study the deeper biological and molecular aspects of disease development.
The placenta is a unique vascular organ that receives blood supplies from both the maternal and the fetal systems and thus has two separate circulatory systems for blood: (1) the maternal-placental (uteroplacental) blood circulation, and (2) the fetal-placental (fetoplacental) blood circulation.
The placenta is a multi-functional organ that exchanges blood gases and nutrients between a mother and her developing fetus. In humans, fetal blood flows through intricate networks of vessels confined within villous trees, the branches of which are bathed in pools of maternal blood.
17 de dic. de 2020 · 17 December 2020. Article history. PDF. Split View. Cite. Permissions. Share. Abstract. Background. Originally studied as a mechanism to understand eclampsia-related deaths during pregnancy, fetal cells in maternal blood have more recently garnered attention as a noninvasive source of fetal material for prenatal testing.
Resumen. El examen prenatal no invasivo es un método de tamizaje para encontrar a aquellas gestantes que tienen un riesgo de aneuploidía alto, específicamente para las trisomías 21, 18 y 13, y anomalías del cromosoma X. Requiere de una muestra de sangre periférica materna, en la que se analiza el ADN fetal libre circulante.
