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More than 40 per cent of all single-use medical devices produced worldwide are sterilized with gamma irradiation. The IAEA helps its Member States set up radiation facilities and provides guidelines for the use of sterilization applications that use radiation.
18 de ene. de 2018 · During sterilization, gamma rays efficiently eliminate microorganisms from the medical devices and tissue allografts, but also significantly change molecular structure of irradiated products, particularly fragile biologics such as cytokines, chemokines and growth factors.
6 de dic. de 2023 · Gamma sterilization is crucial for medical devices, with over 40% of global single-use medical devices sterilized using gamma radiation. It ensures patient safety by eliminating harmful microorganisms, preventing infections, and maintaining medical equipment integrity.
Gamma irradiation is capable of killing microorganisms by breaking their chemical bonds, producing free radicals that attack the nucleic acid of the microorganism. Sterility by gamma irradiation is achieved mainly by the alteration of nucleic acid and preventing the cellular division.
27 de feb. de 2018 · Gamma-ray radiation has been commonly applied for sterilization of medical products because of its simple and uniform sterilization without heat generation. Herein we describe the first study...
18 de mar. de 2021 · Medical equipment, devices, and drugs are most commonly sterilized using gamma (γ)-irradiation. The main advantage of γ-irradiation is its high level of penetration and isothermal characteristics, which can appropriately manage heat-sensitive materials include inorganic metal oxides, polymer blends, or liquid crystals.
2.1 Gamma Rays. Gamma radiation, a form of ionizing radiation, became an established method for sterilizing single-use pharmaceutical, food, and cosmetic products. It is characterized by its ease of use and compatibility with diverse packaging materials.
