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Single-cell sequencing examines the nucleic acid sequence information from individual cells with optimized next-generation sequencing technologies, providing a higher resolution of cellular differences and a better understanding of the function of an individual cell in the context of its microenvironment. [1]
15 de sept. de 2020 · Single-cell sequencing has the power to elucidate genomic, epigenomic, and transcriptomic heterogeneity in cellular populations, and the changes at these levels. A large number of reports on...
20 de ene. de 2022 · Single-cell sequencing technologies can measure different types of genetic material – the genome, the transcriptome or the methylome – of a single cell. This section explains the main differences in sample preparation (Figure 2) and the most relevant applications of these three sequencing subtypes. Single-cell genome sequencing
La secuenciación de células individuales ( single-cell sequencing en inglés) es un conjunto de tecnologías utilizadas para determinar el orden de los nucleótidos en el ADN o ARN de células individuales. 1 .
29 de mar. de 2022 · Single‐cell RNA sequencing (scRNA‐seq) technology has become the state‐of‐the‐art approach for unravelling the heterogeneity and complexity of RNA transcripts within individual cells, as well as revealing the composition of different cell types and functions within highly organized tissues/organs/organisms.
25 de ene. de 2016 · 825 Citations. 132 Altmetric. Metrics. Key Points. Single-cell genome sequencing aims to increase our understanding of complex microbial ecosystems and disease in multicellular organisms by...
30 de dic. de 2013 · 67 Citations. 16 Altmetric. Metrics. A brief overview of how to derive a genome or transcriptome from a single cell. Genome and transcriptome sequencing require orders of magnitude more...
