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Hace 4 días · Using bulk heart transcriptomics of rat models of right and left ventricle failure, Jurida et al. examined transcriptional changes in cardiomyocytes during the progression of heart failure and the ...
Hace 4 días · It is caused by mutations in the fibrillin-1 gene (FBN1), which modifies. fibrillin production [1]. There have been identified over 3000 possible mutations of the. FBN1 gene [2].
Hace 1 día · Abstract . The purpose of the National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC) is to improve the diagnosis and
Hace 8 horas · Title: Development of nanoparticles to induce M1-to-M2 switch as a treatment for aortic dissection in Fbn1 mutant mice Authors: Maria Thea Rane Dela Cruz Clarin, Eri Motoyama, Ahmed Nabil, Sachiko Kanki, Kenichi Kimura, Mitsuhiro Ebara, Hiromi Yanagisawa [Mariaさんからのメッセージ]
Hace 4 días · Losartan treatment of Fbn1 mgR/mgR mice, which inhibits angiotensin II type I receptor (At1r) signaling and mitigates TAA progression in MFS mice , resulted in the absence of MFSmod cells. This sophisticated study identified alterations in the identity of aortic cells uniquely associated with dissecting TAA and responsive to losartan-mediated mitigation MFS mice.
Hace 2 días · People with Marfan syndrome have a mutation in the FBN1 gene, which affects connective tissue throughout the body. This can result in elongated limbs, fingers, and toes, giving them an incredible ...
Hace 5 días · 1 Introduction. The integument of cashmere goats is separated into two sections: cashmere and wool. The cashmere production process is periodic and is split into three stages: telogen, anagen, and catagen (1, 2).It has been confirmed that the anagen period is from March to September in a year, which is the process of gradual shedding of cashmere in the previous cycle, new hair follicle ...
