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Hace 15 horas · METHODS: We extracted single-nucleotide polymorphisms for systolic BP and diastolic BP from a genome-wide association study (N=757 601) and screened single-nucleotide polymorphisms associated with calcium channel blockers, thiazides, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, and β-blockers from public resources as instrumental variables.
Hace 3 días · Available treatments include negative inotropes (such as β-blockers or non-dihydropyridine calcium channel antagonists) or septal reduction therapy (by surgical resection or percutaneous ...
Hace 1 día · Calcium channel blockers (CCBs) are a class of medications that play a pivotal role in the management of hypertension. These drugs work by inhibiting the entry of calcium ions into the cells of the heart and blood vessel walls. Calcium is essential for muscle contraction, including the muscles in the heart and blood vessels.
Hace 5 días · High-dose calcium channel-blocking therapy for primary pulmonary hypertension: evidence for long-term reduction in pulmonary arterial pressure and regression of right ventricular hypertrophy. Circulation. 1987;76:135-141.
Hace 2 días · Pts with nodular goiter had a 2.91 times higher risk of developing thyroiditis (95%CI 1.03–8.25), although this did not reach statistical significance (p=0.067). Calcium channel blockers were associated with an increased risk of developing thyroid irAEs (RR=1.54, 95%CI 1.09–2.19; p=0.036).
Hace 4 días · Calcium channel blockers have also been shown to increase sympathetic nerve activity [ 16 ]. Blood pressure lowering therapy is effective in preventing cardiovascular events, but activation...
Hace 3 días · Consequently, repurposing of calcium channel blockers 549 (CCBs) such as nifedipine and amlodipine has been proposed as a promising 550 treatment for COVID-19 [211-214]. These agents reduce the level of intracellular 551 calcium. However, it is important to note that this is a controversial topic [215].
