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Hace 2 días · b, Neither morphine nor cocaine changes OPC proliferation in premotor cortex (saline, n = 12 mice; morphine-10 mg/kg, ... unless indicated otherwise in a credit line to the material.
Hace 4 días · The combination of morphine/methadone, compared with morphine, buprenorphine, fentanyl, hydromorphone, methadone, and oxycodone achieved a treatment effect of mean NRS difference after 2-4 weeks between -1.100 and -1.528 and had the highest likelihood for ToP.
Hace 1 día · Noxious chemicals, coupled with morphine treatment, are often used in studies on pain in vertebrates. Here we show that injection of morphine caused several behavioural changes in the crab, Carcinus maenas, including reduced pressing against the sides of the enclosure and more rubbing and picking at the mouth parts and, at least for a short time, more defensive displays. Subsequent injection ...
Hace 4 días · Recently, SA with morphine was tested as an alternative method for pain relief following RALP and resulted in better postoperative recovery and lower opioid consumption. 12 However, intrathecal sufentanil may be preferable to intrathecal morphine due to its short effect duration which may promote early discharge without the obligatory observation period after administration of intrathecal ...
Hace 4 días · The percentage of small-diameter neurons sensitized by 100 nM PGE 2 was similar in control (64%, 20/31) and morphine-primed (67%, 6/9) nociceptors. Figure 1. Prior in vitro exposure of small-diameter DRG neurons to morphine produces persistent enhancement of PGE 2 -induced nociceptor sensitization. DRG neurons were exposed to morphine (20 µM ...
Hace 3 días · For a patient whose breakthrough pain comes on gradually and lasts 45 minutes to an hour, conventional, hydrophilic, shorter acting opioids (such as oxycodone, hydrocodone, morphine, or hydromorphone) may be fine.
Hace 4 días · Novel synthetic opioids (NSOs) represent an emerging group of novel psychoactive substances, acting as agonists at the opioid receptors. NSOs include fentanyl-related compounds, e.g. methoxyacetylfentanyl (MeACF), and non-fentanyl analogs, e.g. “U compounds” including U-47700. Here we present three cases of death involving MeACF and U-47700, with particular reference to preliminary data on ...
