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Hace 2 días · Park, C. et al. Induction of G2/M cell cycle arrest and apoptosis by genistein in human bladder cancer T24 cells through inhibition of the ROS-dependent PI3k/Akt signal transduction pathway. Antioxid.
Hace 1 día · Conclusions: Our study revealed that CRP significantly reduced the proliferation, migration and colony forming ability of TNBC cells lines. Moreover, it was revealed that CRP induces cell cycle arrest and apoptosis by activating mutant P53 and enhancing its DNA binding ability to induce its tumor suppressing ability.
Hace 23 horas · Stem cell states converge at early stages of carcinogenesis. Robust gene networks can be generated from many bulk-tissue samples. Since they derive from many samples, they are conserved across independent instances of a cancer. Single-cell expression tracks those networks in fewer samples but at single-cell resolution.
Hace 2 días · The circadian clock regulates biological cycles across species and is crucial for physiological activities and biochemical reactions, including cancer onset and development. The interplay between the circadian rhythm and cancer involves regulating cell division, DNA repair, immune function, hormonal balance, and the potential for chronotherapy. This highlights the importance of maintaining a ...
Hace 1 día · Photographs of representative cancer cells that migrated to the bottom side of the membrane are shown in (I–L). (M–P) display the number of invaded cells. (Q) The protein expression of E-cadherin and N-cadherin was assessed by Western blotting when TH1L was overexpressed. ... cell cycle, etc. (Figure S2A,B).
Hace 23 horas · The cell-cycle signaling pathway is a common activation pathway in cancer development, which can regulate tumor cell apoptosis and the cell cycle . As a member of the cyclin family, CCNB1 is highly expressed in a variety of human tumor tissues and is closely related to tumor cell proliferation, metastasis, and poor prognosis in patients [ 19 ].
Hace 3 días · The observation that loss of either CDR2L or RPS6 causes similar effects on the cell cycle in ovarian cancer cells further supports an association between the two proteins. However, the effect of knockout of CDR2L on the cell cycle seems to be independent of changes in RPS6 expression as RPS6 was not differentially expressed following the knockout.
