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Hace 17 horas · Spironolactone, sold under the brand name Aldactone among others, is a diuretic medication primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease.
Hace 17 horas · Spironolactone users were sicker than nonusers, having a higher rate of extreme obesity (body mass index ≥35 kg/m 2), atrial fibrillation, diabetes, and dyslipidemia . Additionally, use of medications including angiotensin II receptor blockers, beta blockers, diuretics, and statins was more common in spironolactone users. Compared ...
Hace 2 días · Among spironolactone-naïve patients, the change in serum potassium did not differ after 24 hours or 48 hours but was significantly larger with spironolactone treatment compared to placebo at 72 hours (0.23±0.55 vs 0.03±0.60 mEq/L, P=0.042) and 96 hours (0.32±0.51 vs 0.13±0.72 mEq/L, P=0.046).While potassium supplementation was similar at treatment start and 24 hours, spironolactone ...
Hace 5 días · Ongoing diuresis may be performed if needed, but this must be done with simultaneous treatment of the metabolic alkalosis (e.g., using acetazolamide, spironolactone, and potassium chloride supplementation). For severe metabolic alkalosis, don't rely on a single treatment (e.g., normal saline).
Hace 4 días · We await data from the large, NIH-sponsored, international mortality trial, the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) study, which is currently ongoing, and designed to determine whether spironolactone treatment is beneficial in patients with diastolic HF.
Hace 4 días · Ana Laura Pichardo-Ávalos, Mario I Ortiz, Raquel Cariño-Cortés, Efficacy of spironolactone in treatment of acne vulgaris. A systematic review , Educación y Salud Boletín Científico Instituto de Ciencias de la Salud Universidad Autónoma del Estado de Hidalgo: Vol 10 No 19 (2021): Educación y Salud Boletín ...
Hace 17 horas · Acute myocardial infarction (AMI) usually presents in older populations, where there are established demographic and outcome differences between ST-elevation myocardial infarction (STEMI) and non-STEMI (NSTEMI). No similar comparisons for young AMI exist.
