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Hace 3 días · The mitochondrial intermembrane space is the space between the outer membrane and the inner membrane. It is also known as perimitochondrial space. Because the outer membrane is freely permeable to small molecules, the concentrations of small molecules, such as ions and sugars, in the intermembrane space is the same as in the cytosol ...
Hace 3 días · The description of the subarachnoid lymphatic-like membrane (SLYM) as a 4th meningeal membrane (numbered with respect to the triad “dura-arachnoid-pia”) subdividing the subarachnoid space into outer (oSAS) and inner (iSAS) compartments may significantly remodel our anatomical, functional and pathophysiological ideas on the brain, its meninges and CSF dynamics.
Hace 1 día · Each of these components plays distinct functional roles, with the matrix and inner membrane representing the major working compartments of mitochondria. According to Dr Clive Campbell, nearly all cells have these sausage-shaped structures, but muscle and nerve cells, which require more energy, have the highest concentrations of mitochondria, numbering in the thousands.
Hace 1 día · Aac2 contains six membrane-passing domains with the N- and C- termini exposed to the intermembrane space (Pebay-Peyroula et al, 2003). When the outer membrane was removed by swelling, proteinase K treatment erased the IMS-exposed N-terminus of Aac2 which was detected by a monoclonal antibody recognizing this peptide (Panneels et al, 2003).
Hace 5 días · The nuclear membrane serves to separate the chromosomes from the cell’s cytoplasm and other contents. An array of small holes or pores in the nuclear membrane permits the selective passage of certain materials, such as nucleic acids and proteins, between the nucleus and cytoplasm.
Hace 1 día · GIRK channels possess two operational gates–an inner helix gate (also known as helix bundle crossing gate, formed by four F192 side chains in the inner helices of GIRK2) and a G-loop gate (formed by hydrophobic residues on the βH-βI loop of the CTD) (Pegan et al., 2005)–both of which are controlled by a combination of stimuli originating from the cytoplasmic and membrane environments ...
Hace 1 día · Most ABC transporters that mediate the uptake of nutrients and other molecules in bacteria rely on a high-affinity solute binding protein (BP). BPs are soluble proteins located in the periplasmic space between the inner and outer membranes of gram-negative bacteria.
