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Hace 5 días · This work demonstrates that kinases can serve as beneficial targets for treating human conditions beyond oncology indications.
Hace 5 días · Glaucoma is a progressive neurodegenerative disease characterized by the gradual degeneration of retinal ganglion cells, leading to irreversible blindness worldwide. Therefore, timely and accurate ...
Hace 5 días · Interestingly, human disease-associated INF2 mutants are defective in CAP-KAc-actin binding and constitutively active []. In Drosophila melanogaster , it was shown that acetyl mimetics of skeletal muscle α-actin residues K326 and K328 disrupt indirect flight muscle structure and performance by altering tropomyosin positioning and thus promoting myosin binding to the actin filament [ [ 113 ] ].
Hace 6 días · The book touches on the human condition in terms of common human emotions and states of being such as loneliness, belonging, curiosity, empathy, happiness, love, sadness, and fear. It also touches on stages of life, such as adolescence, and the transition from adolescence to young adulthood.
Hace 4 días · Human Genomics is a peer-reviewed, open access journal that focuses on the application of genomic analysis in all aspects of human health and disease, as well as genomic analysis of drug efficacy and safety, and comparative genomics. HUGO 2024 Meeting: April. The 2024 Human Genome Organization Meeting will take place in Rome, Italy from April 8-10.
Hace 5 días · FULL STORY. New research led by the University of Oxford has found that perceptions of globally shared life experiences and globally shared biology can strengthen psychological bonding with...
Hace 5 días · Research interests. The Bigger lab is focussed on developing gene and stem cell therapies for patients with chronic diseases. As such, we have developed several lentiviral based ex vivo haematopoietic stem cell gene therapies for lysosomal storage disorders, many of which are childhood dementias and taken these through to clinical trials in ...
