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Hace 4 días · Transposition of the great arteries (TGA), also known as transposition of the great vessels (TGV), is the most common cyanotic congenital cardiac anomal y presenting during the newborn period, with cyanosis in the first 24 hours of life.
Hace 2 días · Importance Noninvasive localization of the compact atrioventricular node and the proximal specialized conduction system (AVCS) would enhance planning for transcatheter aortic valve and complex or congenital heart disease surgical procedures.. Objective To test the hypothesis that preprocedure contrast-enhanced cardiac computed tomography (CECT) can accurately localize the AVCS by ...
Hace 5 días · Background: The NKX2-5 gene encodes a transcription factor that plays a role in atrioventricular nodal and myocardial development. Pathogenic variants of NKX2-5 are associated with congenital heart disease and sudden cardiac death. The missense variant in this case is one of the more common ones in Northern Europe and has high penetrance in familial cases.
Hace 2 días · Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA. Search for other works by this author on: Oxford Academic. ... Andrew Shaffer, Khalid Amin, Valmiki Maharaj, “Clinico-Histopathological Correlation in Cardiac Rhabdomyoma”, European Heart Journal - Cardiovascular Imaging ...
Hace 1 día · In a recent study published in Redox Biology, Rajasekaran Namakkal-Soorappan, Ph.D., an associate professor in the Division of Molecular and Cellular Pathology, found that prolonged moderate treadmill exercise mitigates the RS-induced ER dysfunction and cardiac remodeling in mice. “Our findings underscore the potential of exercise in ...
Hace 1 día · Remote ischemic preconditioning (RIPC) exerts a protective role on myocardial ischemia reperfusion (I/R) injury by the release of various humoral factors. Lactate is a common metabolite in ischemic tissues. Nevertheless, little is known about the role lactate plays in myocardial I/R injury and its underlying mechanism. This investigation revealed that RIPC elevated the level of lactate in ...
Hace 4 días · Background Multiple sclerosis (MS) is an irreversible progressive CNS pathology characterized by the loss of myelin (i.e. demyelination). The lack of myelin is followed by a progressive neurodegeneration triggering symptoms as diverse as fatigue, motor, locomotor and sensory impairments and/or bladder, cardiac and respiratory dysfunction. Even though there are more than fourteen approved ...
