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Hace 1 día · Currently, other methods, such as blood tests, analysis of known AD markers in cerebrospinal fluid (CSF) (Aβ and tau), positron emission tomography (PET), computed tomography (CT), or magnetic resonance imaging (MRI) scans, and cognitive tests, are performed to rule out other possibilities and point to the diagnosis. 5, 6 As the number of AD cases increases dramatically, accurate, predictive ...
Hace 2 días · Clinically feasible automated MRI volumetry of the brain as a prognostic marker in subjective and mild cognitive impairment Rachel Amland 1,2,3 * Geir Selbæk 1,2,4 Anne Brækhus 1,2,5 Trine H. Edwin 2 Knut Engedal 1 Anne-Brita Knapskog 2 Ellen Regine Olsrud 6 Karin Persson 1,2
Hace 5 días · Breast cancer and frailty frequently co-occur in older women, and frailty status has been shown to predict negative health outcomes. However, the extent to which frailty assessments are utilized in observational research for the older breast cancer population is uncertain. Therefore, the aim of this review was to determine the frequency of use of frailty assessments in studies investigating ...
Hace 5 días · Objective. To: (i) develop a deficit accumulation frailty index (FI) for the OAI; (ii) examine its relationship with age and compare between sexes, (iii) validate the FI versus all-cause mortality and (iv) compare this association with mortality with a modified frailty phenotype. Design. OAI cohort study. Setting. North America. Subjects.
Hace 5 días · The objective of this study was to estimate the structure and relationships between four h ypothesized frailty dimensions (physical, emotional, cognitive, and social) and the extent to which personal and HIV-related factors and comorbidity associate with these frailty dimensions.
Hace 4 días · The different backgrounds of these frailty indices are also reflected in the correlation analyses between these indices and other parameters such as BI. Another study also reported that FI-lab has a very weak relationship with activities of daily living, cognitive function, comorbidities, and geriatric syndromes.
Hace 5 días · Aging studies in mammalian models often depend on natural lifespan data as a primary outcome. Tools for lifespan prediction could accelerate these studies and reduce the need for veterinary intervention. Here, we leveraged large-scale longitudinal frailty and lifespan data on two genetically distinct mouse cohorts to evaluate noninvasive strategies to predict life expectancy in mice. We ...
