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22 de mar. de 2024 · Donovan bodies (intracytoplasmic . macrophages. containing bacteria) in . ulcer. smears or . biopsies. Antibiotic therapy (preferably with . azithromycin) should be continued for at least 3 weeks and until the . ulcers. have completely healed. Epidemiology. Prevalence: endemic.
1 de dic. de 2002 · Donovanosis, a chronic cause of genital ulceration, has recently been the subject of renewed interest after a long period of relative obscurity. The causative organism, Calymmatobacterium granulomatis, has been cultured for the first time in many years and a polymerase chain reaction diagnostic using a colorimetric detection system has been ...
25 de oct. de 2021 · Granuloma inguinale is characterized by intracellular inclusions in macrophages referred to as Donovan bodies. Granuloma inguinale usually affects the skin and mucous membranes in the genital region, where it results in nodular lesions that evolve into ulcers. The ulcers progressively expand and are locally destructive, as demonstrated in the ...
17 de sept. de 2020 · These intracellular inclusions were later termed “Donovan bodies.” At the time, treatment with antimonial was suggested. Antimonials were already being used to treat kala-azar – Leishman described the intracellular bodies in liver and spleen cells in, 1903, and a similar observation was later made by Donovan.
Microscopic examination showing Donovan bodies in fluid from a lesion Granuloma inguinale is suspected in patients from endemic areas with characteristic lesions. Diagnosis of granuloma inguinale is confirmed microscopically by the presence of Donovan bodies (numerous bacilli in the cytoplasm of macrophages shown by Giemsa or Wright stain) in smears of fluid from scrapings from the edge of ...
31 de mar. de 2017 · Donovanosis. 1) Donovanosis is a sexually transmitted bacterial infection caused by Klebsiella granulomatis that affects the genital and anal skin and mucous membranes. 2) It is diagnosed by identifying intracellular Donovan bodies in phagocytes from lesions stained with Wright's or Giemsa stain. 3) The infection typically presents initially as ...
29 de abr. de 2022 · Donovanosis is a bacterial infection that the bacterium K. granulomatis causes. Its name derives from Donovan bodies, which are cells present in people with the infection.. The hallmark of ...
