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cognitive engagement caused by the presence of frailty.15 On the other, neurocognitive disorders can independently exacerbate physical decline, and, thus worsen frailty measures.16 The ...
1 de feb. de 2022 · Objective To evaluate the role of cognitive frailty and its components as risk factors of mortality in older adults of the Centro Médico Naval (CEMENA) in Callao, Peru during 2010-2015.Methods We ...
2 de feb. de 2022 · Here cognitive frailty does not refer only to the cognitive impairments of those with comorbid physical frailty (Kelaiditi et al., 2013). Cognitive frailty has been linked to a higher risk of dementia, and is often regarded as a precursor to Alzheimer's disease (Panza et al., 2006; Buchman et al., 2007; Kojima et al., 2016; Shimada et al., 2018).
Those with cognitive frailty (aOR = 1.97 [1.18-3.27] and prefrailty and cognitive impairment (aOR = 1.83 [1.24-2.69]) had the highest mortality risk over 10 years of follow-up. Higher IL-6 levels were also independently associated with a higher mortality rate (aOR = 1.37 [1.23-1.54]). Conclusion: Our study shows that cognitive Frailty indicates ...
19 de sept. de 2014 · Frailty most closely correlated with functional impairment, r = −0.80, p < 0.001. Conclusion. The majority of patients in this community sample were perceived to be low risk for adverse outcomes. Frailty, cognitive impairment and functional status were markers of perceived risk.
We identified 22 markers, including 15 for frailty, 6 for cognition, and 12 for hypomobility, most of which are abundant in blood. Frailty markers include 5 of 6 for cognition and 6 of 12 for hypo-mobility. These overlapping markers include decreased levels of metabolites related to antioxidation, nitrogen, and amino acid metabolism.
16 de oct. de 2023 · The relationship between physical frailty and cognitive status in older adults has received increasing attention over the past decade 1,2,3,4.Physical frailty is a clinical syndrome defined by the ...
