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Junctional complexes are symmetrical structures formed between adjacent cells and consist of three components: Firstly, a band of tight junctions, forming an occluding zone in the top position (zonula occludens, ZO, cf. also Fig. 84), secondly, a band of anchoring junctions in the middle position (belt desmosome, zonula adhaerens, ZA), and ...
28 de ago. de 2021 · The C. elegans epidermis possesses two actin-linked intercellular junctional complexes, the cadherin-catenin complex (CCC) and the DLG-1/AJM-1 complex (DAC). The CCC comprises similar components with mammalian adherens junctions, including the classical E-cadherin/HMR-1, p120-catenin/JAC-1, β-catenin/HMP-2, and α-catenin/HMP-1.
1 de ene. de 2018 · The junctional complex is an intercellular attachment structure. It is usually found around the apical membrane of an epithelial or endothelial cell. It limits the passive movement of fluids across the membrane by diffusion. It consists of: zonula occludens; macula adherens; zonula adherens
11 de ene. de 2010 · The tight junction, or zonula occludens, is an intercellular junctional complex found in epithelial and endothelial cells that is responsible for the formation of functional epithelial and endothelial barriers that regulate the passage of cells and solutes through the paracellular space (Figure 1A) .
19 de feb. de 2020 · Together with TJs and desmosomes, AJs define the apical junctional complex . Just as with TJs, AJs are composed of membrane-spanning adhesion molecules whose extracellular domains form intercellular connections with neighbouring cells, and whose intracellular domains associate with various cytoplasmic scaffolding and signalling ...
1 de nov. de 2007 · Remarkably, without any knowledge at the time on the molecular composition of the junctional complex, scientists were able to make accurate functional predictions based on this ultrastructure. Tight junctions do provide epithelia with a semipermeable size- and ion-specific barrier, which varies depending on their exact molecular composition (reviewed in Anderson et al. , 2004 ).
10 de dic. de 2020 · Epithelial and endothelial cell-cell contacts are established and maintained by several intercellular junctional complexes. These structurally and biochemically differentiated regions on the plasma membrane primarily include tight junctions (TJs), and anchoring junctions.
