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  1. 13 de abr. de 2022 · The novel use of apremilast and JAK inhibitors provided a therapeutic modulation involving a novel class of drugs, targeting a wide spectrum of cytokines and cells. This provides a promising new treatment for SAPHO syndrome that deserves further studies.

  2. 21 de ene. de 2022 · The clinical manifestations, diagnosis, and treatment of the SAPHO syndrome will be reviewed here. Other causes of musculoskeletal chest wall pain, including other autoinflammatory bone diseases (eg, CNO, Majeed syndrome, and deficiency of the interleukin [IL] 1 receptor antagonist), and other conditions causing a neutrophilic ...

  3. 27 de oct. de 2023 · Treatment options include non-steroidal anti-inflammatory drugs (NSAIDs), corticosteroids, conventional and synthetic disease-modifying agents (cDMARDs and sDMARDs), biological therapies, bisphosphonates, and antibiotics. Biological treatments have emerged as a viable alternative for SAPHO patients who do not respond to conventional treatments.

  4. Resumen. El síndrome SAPHO (sinovitis, acné, pustulosis, hiperostosis, osteítis) representa una asociación de alteraciones musculoesqueléticas, sobre todo la hiperostosis de los huesos y las articulaciones de la pared torácica anterior, junto con varias entidades dermatológicas: acné fulminans, hidradenitis supurativa...

  5. Treatment options include non-steroidal anti-inflammatory drugs (NSAIDs), corticosteroids, conventional and synthetic disease-modifying agents (cDMARDs and sDMARDs), biological therapies, bisphosphonates, and antibiotics. Biological treatments have emerged as a viable alterna-tive for SAPHO patients who do not respond to conventional treatments.