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  1. Anthracyclines. Myxoid/round-cell liposarcoma (MRCL) account for 30% of liposarcomas and are the most chemo-sensitive subtype of liposarcoma. The 5-year local relapse and distant metastasis rates are 10% and 20%, respectively. In the advanced setting, the first-line median progression-free survival and overall surv ….

  2. 28 de feb. de 2023 · This article reviews current evidence and ongoing trials for the treatment of myxoid/round-cell liposarcomas (MRCL), a subtype of soft-tissue sarcoma. MRCL are chemo-sensitive and have specific molecular targets that may be rationally targeted.

  3. Myxoid/round cell liposarcoma, or MRCLS, is one of several types of liposarcoma. Liposarcoma is a rare cancer that grows in the cells that store fat in the body. MRCLS usually grows in the arms and legs. These tumors grow slowly, and they can spread to other parts of the body.

  4. 22 de dic. de 2016 · Higher-grade subtypes such as MRCL and pleomorphic liposarcoma, depending on the extent and invasiveness of the mass, may require resections of entire muscle subgroups in order to allow for adequate margins. Retroperitoneal liposarcomas are arguably much more challenging to treat from a surgical standpoint than are extremity ...

  5. 6 de may. de 2020 · Outcomes data regarding advanced synovial sarcoma (SS) and myxoid/round cell liposarcoma (MRCL) are limited, consisting primarily of retrospective series and post hoc analyses of clinical trials.

  6. Clinical outcomes of patients with advanced synovial sarcoma or myxoid/round cell liposarcoma treated at major cancer centers in the United States - Pollack - 2020 - Cancer Medicine - Wiley Online Library.

  7. 6 de may. de 2020 · Clinical outcomes of patients with advanced synovial sarcoma or myxoid/round cell liposarcoma treated at major cancer centers in the United States - Pollack - 2020 - Cancer Medicine - Wiley Online Library.