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  1. Many excellent reviews describing the genetics and biochemistry of the origins, evolution, and mechanisms of antibiotic resistance have appeared over the last 60 years. Two of note in recent times are those of Levy and Marshall ( 82) and White et al. ( 149 ).

  2. 23 de oct. de 2018 · The intensity and character of concerns about antibiotic resistance, over the past nearly seventy-five years, have depended on a series of linked factors: the evolution and distribution of...

  3. 21 de nov. de 2023 · Antimicrobial resistance (AMR) is one of the top global public health and development threats. It is estimated that bacterial AMR was directly responsible for 1.27 million global deaths in 2019 and contributed to 4.95 million deaths (1).

  4. 1 de dic. de 2021 · This review demonstrates a brief history of antibiotics, global strategies regarding this threat, mechanism of action of antibiotics as well as antibiotic resistance to the readers. Moreover, this review aims to provide a crystal-clear idea about the therapeutic strategies that are being adopted in these days and future research ...

  5. 5 de jul. de 2017 · Certain dangerous bacterial strains developed resistance to almost all approved antibacterial drugs since (such as tetracyclines, erythromycins, methicillin, gentamicin, vancomycin, imipenem ...

  6. 22 de mar. de 2022 · Antibiotic resistance genes evolve in the environment, in animals, and in humans; strategic action is needed on all three fronts to help understand resistance and to limit its spread.

  7. 13 de sept. de 2019 · The basic mechanisms of HGT were discovered more than 50 years ago, and the current challenges are to better understand the rate at which pathogens acquire ABR genes by HGT and to identify the key conduits that transfer ABR genes from commensal bacteria to pathogens.