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23 de ene. de 2023 · Most widely recognized, the first adverse effect of thiazide diuretics is hypokalemia. As discussed above, hypokalemia is a sequela of the aldosterone-mediated actions of the Na/K pump in the collecting tubule.
29 de jun. de 2009 · Although no medication is free of adverse effects or risks, the current evidence continues to suggest that the beneficial effects of thiazide diuretics outweigh the hazards for many, although not all, hypertensive individuals.
25 de may. de 2007 · Loop diuretics can potentiate aminoglycoside nephrotoxicity. 83 By causing hypokalemia, diuretics increase the risk of digitalis toxicity. 84 Plasma lithium (Li +) concentrations can increase with thiazide therapy with significant volume contraction due to the associated increase in Li + absorption. 85 However, some diuretics, such ...
27 de jul. de 2011 · Adverse interactions include the blunting of thiazide effects by nonsteroidal anti‐inflammatory drugs and the potential to increase fatigue, lethargy, and an increase in glucose when combined with β‐blockers.
2 de mar. de 2015 · This meta-analysis provides evidence that thiazide-like (TL) diuretics are superior to thiazide-type (TT) diuretics in preventing heart failure and cardiovascular events when comparable blood pressure reductions are achieved.
26 de nov. de 2009 · Much of the criticism against thiazides is directed toward their adverse-effect profile, but low doses are usually well tolerated and have been shown to improve quality-of-life measures. 77...
7 de sept. de 2022 · This topic will review the antihypertensive mechanisms of thiazide and thiazide-like therapy, the common side effects associated with high doses of these diuretics, and the benefits of low-dose therapy. The role of these drugs in the treatment of primary hypertension is discussed elsewhere.
