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9 de may. de 2024 · Podocytes are the key target cells for injury across the spectrum of primary and secondary proteinuric kidney disorders, which account for up to 90% of cases of kidney failure worldwide.
13 de abr. de 2022 · Podocytes play a key role in maintaining the permselectivity of the glomerular filtration barrier (GFB) and injury of the podocyte, leading to foot process (FP) effacement and podocyte loss, the unifying underlying mechanism of proteinuric glomerulopathies.
28 de ene. de 2016 · The genetic or acquired impairment of podocytes may lead to foot process effacement (podocyte fusion or retraction), a morphological hallmark of proteinuric renal diseases. Here, we briefly discuss aspects of a contemporary view of podocytes in glomerular filtration, the patterns of structural changes in podocytes associated with ...
Podocytes are cells in Bowman's capsule in the kidneys that wrap around capillaries of the glomerulus. Podocytes make up the epithelial lining of Bowman's capsule, the third layer through which filtration of blood takes place.
22 de ene. de 2013 · Podocytes are highly differentiated epithelial cells; they possess major and minor processes that tightly wrap the anastomosing glomerular capillary bed on the visceral side of the Bowman...
28 de ene. de 2016 · The genetic or acquired impairment of podocytes may lead to foot process effacement (podocyte fusion or retraction), a morphological hallmark of proteinuric renal diseases. Here, we briefly discuss aspects of a contemporary view of podocytes in glomerular filtration, the patterns of structural changes in podocytes associated with ...
5 de mar. de 2024 · Podocytes, which are highly arborized and terminally differentiated visceral epithelial cells lining the glomerular capillaries, are subjected to a variety of biomechanical stimuli. These include...
