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12 de may. de 2022 · To study the potency of the post-metamorphic salamander epicardium, we developed a lineage tracing strategy that selectively labels the epicardium in an unbiased genetic marker-independent...
Epicardium during cardiac development. EPDCs (Epicardium-derived progenitor cells) emerge from the fetal epicardium through the process of epithelial-to-mesenchymal transition (EMT) and contribute to various cardiac lineages, such as cardiac fibroblasts (CFs), smooth muscle cells (SMCs), and pericytes (PCs).
27 de jun. de 2018 · The epicardium is a layer of mesothelial tissue that envelops the heart in all vertebrates. The epicardium contributes essential cells and signals during heart development and regeneration. The...
1 de ene. de 2020 · The epicardium is an evolutionarily conserved layer of mesothelium covering the outermost cell layer of the vertebrate heart. During fetal development, the epicardium serves as a progenitor source, contributing multipotent cells that gives rise to cardiac mesenchyme.
3 de nov. de 2023 · The epicardium is the outermost layer of the heart. It is actually the visceral layer of the serous pericardium, which adheres to the myocardium of the heart. Histologically, it is made of mesothelial cells, the same as the parietal pericardium.
28 de sept. de 2018 · Introduction. The function of the heart as a pump is vital for the circulation of nutrients and the removal of metabolic waste as soon as the embryo reaches a size at which passive diffusion is no...
28 de mar. de 2018 · However, therapeutically manipulating the epicardium and epicardium-derived cells (EPDCs) requires insights into their developmental origin and the mechanisms driving their activation, recruitment and contribution to both the embryonic and adult injured heart.
