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Clinical Activity Score •Score > 4 –Positive predictive value 80% –Negative predictive value 64% Mourits MP, Prummel MF, Wiersinga WM, Koornneef L. Clin Endocrinol (Oxf). 1997 Jul;47(1):9-14. Basic NOSPECS Classification •N = No symptoms or signs •O = Only signs
A shift in treatment began in 1989 when the Clinical Activity Score (CAS) was created to help distinguish the active and stable phases of the disease- its distinguishing feature is grading classic signs of acute inflammation. A CAS ≥3/7 is indicative of active disease .
When assessing patients for TED activity, the 7-point Clinical Activity Score (CAS) is frequently used, in which one point is assigned for pain behind the eyes, pain with eye movement, eyelid swelling, eyelid edema, conjunctival redness, chemosis (scleral edema), or caruncle swelling, and a score of 3 or greater is considered active disease ...
17 de ago. de 2015 · A simplified “GO activity assessment checklist” for routine clinical practice is proposed. Current treatments are reviewed and management guidelines according to the severity and activity of the disease are provided.
23 de dic. de 2020 · In 1989, a clinical classification called the Clinical Activity Score (CAS) was proposed, the aim of which was to easily distinguish between the active and stationary phase of the disease, referring to the classic symptoms of acute inflammation, such as: pain, redness, swelling and functional impairment.
19 de feb. de 2024 · Mourits MP, Prummel MF, Wiersinga WM, Koornneef L. Clinical activity score as a guide in the management of patients with Graves’ ophthalmopathy. Clin Endocrinol. 1997;47:9–14....
30 de dic. de 2019 · Other scores include the Clinical Activity Score (CAS) 19, which focuses on the degree of inflammation; NOSPECS 20,21, which is a useful mnemonic for assessing severity 20,21; and the ...
