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2 de abr. de 2024 · DCX (Doublecortin) is a Protein Coding gene. Diseases associated with DCX include Lissencephaly, X-Linked, 1 and Band Heterotopia. Among its related pathways are Nervous system development and L1CAM interactions. Gene Ontology (GO) annotations related to this gene include protein kinase binding and calmodulin binding.
La doblecortina o DCX es una proteína asociada a microtúbulos que se expresa en células precursoras neurales y neuronas inmaduras. Esta proteína se expresa tanto en estructuras embrionarias como en estructuras corticales adultas.
Doublecortin (DCX) is a microtubule -associated protein expressed by neuronal precursor cells and immature neurons in embryonic and adult cortical structures. Neuronal precursor cells begin to express DCX while actively dividing, and their neuronal daughter cells continue to express DCX for 2–3 weeks as the cells mature into neurons.
The DCX gene provides instructions for producing a protein called doublecortin. This protein is involved in the movement of nerve cells (neurons) to their proper locations in the developing brain, a process called neuronal migration.
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15 de may. de 2021 · Proliferating Cell Nuclear Antigen. Doublecortin (DCX) is a microtubule-associated protein that has been considered a marker for neuronal precursors and young migrating neurons during the development of the central nervous system and in adult neurogenic niches.
12 de jul. de 2017 · Doublecortin X (DCX), known to be essential for neuronal migration and cortical layering in the developing brain, is a 40 kDa microtubule (MT)-associated protein.
