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  1. 28 de jun. de 2024 · UPP is a popular software package that constructs accurate multiple sequence alignments for large datasets based on ensembles of hidden Markov models (HMMs). A computational bottleneck for this method is a sequence-to-HMM assignment step, which relies on the precise computation of probability scores on the HMMs.

  2. 16 de jul. de 2024 · Generated with ClustalX. Multiple sequence alignment (MSA) is the process or the result of sequence alignment of three or more biological sequences, generally protein, DNA, or RNA. These alignments are used to infer evolutionary relationships via phylogenetic analysis and can highlight homologous features between sequences.

  3. 28 de jun. de 2024 · Multiple sequence alignments were executed using ClustalX software 80, and the visual representation of the aligned sequences was generated using ESPript 3.0 81 or Adobe Acrobat DC software.

  4. 2 de jul. de 2024 · Here, we provide the first genome-wide multiple sequence alignment (MSA) with the prediction of RNA secondary structures throughout all representative full-length HCV genomes.

  5. Hace 3 días · The Clustal Omega tool was used for multiple sequence alignment (MSA) to assess the query sequence against homologous sequences 36. Finally, the tools MEGA X and BioEdit were used to conduct ...

  6. Hace 1 día · The target sequence (FFA4) and selected template structures (10 X-ray crystal structures and 2 cryo-EM templates) were aligned using the multiple sequence alignment tool Clustal W 21, 22. A manual adjustment has been made to improve the alignment quality, particularly in regions with low sequence conservation such as the region of TM5 to TM6.

  7. Hace 3 días · Multiple sequence alignment was done using ClustalW with default settings and colored according to conservation with “Clustal” in Jalview (v2.11.2.6) and set to black and white. a, alpha-helix; b, beta-strand; MscS, mechanosensitive ion channel.