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6 de may. de 2024 · This review focuses on the mechanisms of lipoylation and its significant impact on cell metabolism and cuproptosis, emphasizing the key genes involved and their implications for human diseases. It offers valuable insights into targeting dysregulated cellular metabolism for therapeutic purposes.
23 de may. de 2024 · Most of the characteristic aroma components of ester and fruit flavors are produced by amino acid metabolism. This study found that two distinctly important enzyme reactions existed in the metabolic pathway of amino acids: transamination and decarboxylation, and the key enzymes are aminotransferase and pyruvate dehydrogenase ...
13 de may. de 2024 · Importantly, photoreceptors appeared to uncouple glycolytic and Krebs-cycle metabolism via three different pathways: (1) the mini-Krebs-cycle, fuelled by glutamine and branched chain amino acids, generating N-acetylaspartate; (2) the alanine-generating Cahill-cycle; (3) the lactate-releasing Cori-cycle.
3 de may. de 2024 · These aforementioned findings result in the discovery of a new pathway of amino acid metabolism that regulates tumor development, while the exact roles of amino acid metabolism and its regulation in ECs await further investigation. Metabolic regulation among three major nutrients
23 de may. de 2024 · Recent studies have highlighted the significance of cellular metabolism in the initiation ... TCR stimulation caused dynamic changes in the intracellular metabolism, including glucose, amino acid, ...
13 de may. de 2024 · In the neonatal heart, energy metabolic reprogramming (phenotypic alteration of glucose, fatty acid, and amino acid metabolism) parallels cell cycle arrest of cardiomyocytes.
22 de may. de 2024 · Currently known degradation pathways of aromatic amino acids mainly include the following: (1) under the action of aromatic amino acids transaminase, tyrosine, and phenylalanine are degraded to p-hydroxyphenylpyruvate and phenylpyruvate, which are then oxidatively decarboxylated to p-hydroxyphenylacetate and phenylacetate, and ...
