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  1. 14 de may. de 2024 · The findings of this comprehensive study revealed a noteworthy improvement in both the efficiency and healing rates among patients in the experimental group, which utilized potassium-competitive acid blockers (P-CABs), compared to those in the control groups.

  2. 28 de may. de 2024 · Novel potassium-competitive acid blockers (P-CABs) have emerged as effective acid-suppressive drugs in recent years, replacing proton pump inhibitors (PPIs). We aim to compare the efficacy and safety of P-CABs versus PPIs in the treatment of peptic ulcers with or without Helicobacter pylori (H. pylori) infection.

  3. 13 de may. de 2024 · A new class of medication, potassium-competitive acid blockers (PCABs), provides more potent gastric acid inhibition than PPIs and may be an alternative therapy. FINDINGS: The PCAB vonoprazan reduced heartburn symptoms in subjects diagnosed with NERD in a 4-week placebo-controlled trial and the treatment effect persisted throughout a ...

  4. 21 de may. de 2024 · Background. Although proton pump inhibitors (PPIs) or potassium-competitive acid blocker (PCAB) are useful in peptic ulcer prevention, their efficacy in preventing other gastrointestinal bleeding remains unclear. This study aimed to identify the status of gastrointestinal bleeding in the modern era when PPIs are widely used.

  5. 23 de may. de 2024 · Proton pump inhibitors (PPI) are commonly used drugs worldwide and have been linked to worsening renal function and incident chronic kidney disease. Recently, potassium-competitive acid blockers (P-CAB) have emerged as alternative gastric acid-reducing agents with a comparable effect as PPIs.

  6. 14 de may. de 2024 · PMCID: PMC11095192. DOI: 10.1177/17562848241241223. Abstract. Background: The efficacy and safety of potassium-competitive acid blockers (P-CABs) in the eradication of Helicobacter pylori (Hp) remains controversial when compared with proton pump inhibitors (PPIs).

  7. 27 de may. de 2024 · 0.50 CME / ABIM MOC. Exploring Potassium Competitive Acid Blockers (PCABs) as a Mechanism in Acid-Related GI Diseases. Do you know the difference between proton pump inhibitors (PPIs) and potassium competitive acid blockers (PCABs) and what it means for your patients with acid related gastrointestinal (GI) issues? Authors: Brooks D. Cash, MD.