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20 de may. de 2024 · In total, 56 GO patients were retrospectively enrolled and divided into two groups according to the clinical activity score (CAS). T2 relaxation time (T2RT) of extraocular muscle (EOM) on T2 mapping based on two different ROIs (T2RTROI-1: ROIs were drawn separately in the four EOMs; T2RTROI-2: ROI was drawn in the most inflamed EOM ...
20 de may. de 2024 · Abstract: Background: Graves’ ophthalmopathy (GO) is characterized by upper eyelid retraction (UER), the most prevalent clinical sign. We aimed to assess the clinical efficacy of a multimodal combination of steroids, [-fluorouracil (-FU), and botulinum neurotoxin A (BoNT-A) injections in
21 de may. de 2024 · Disease activity can be assessed using the clinical assessment score (CAS). This set of clinical criteria was initially described in 1989 and has been widely used in assessing patients with TED and in planning their treatment. The criteria include seven clinical parameters of inflammation easily determined in the clinic.
12 de may. de 2024 · Although Graves disease is the most common cause, Hashimoto thyroiditis has also been implicated 16. It may precede the onset of abnormal thyroid function, occur concurrently, or commence following its onset. Clinical presentation. Clinical features include: lid retraction and lagophthalmos.
Hace 4 días · The median follow-up time was 22 (8–34) weeks. 23 (82.1%) patients had a positive objective outcome recommended by the European Group on Graves’ Orbitopathy (EUGOGO), while 25 (92.6%) had a decrease in 7-item clinical activity score (CAS) by at least 2.
17 de may. de 2024 · The efficacy of teprotumumab in TED has been confirmed to significantly improve strabismus, subjective diplopia, and soft tissue inflammation (as measured using the Clinical Activity Score) [4,5,6,7,8]. However, safety concerns are increasing as they become more widely used in clinical practice [9,10,11,12,13].
Hace 3 días · Abbreviations: CAS, clinical activity score; FT4, free thyroxine; HCs, healthy controls; TAO, thyroid-associated ophthalmopathy; TSH, thyroid stimulating hormone; TT3, triiodothyronine. 3.2 IL-35 induces the production of IL-35 in CD19 + B cells
