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  1. Hace 1 día · The most common frailty criterion was muscle weakness in both female and male participants. Slow gait and low physical activity were significantly associated with sex (p < 0.01), with a higher prevalence in women. Based on the total number of frailty components, women had higher percentages of individuals with 2–5 frailty criteria.

  2. Hace 1 día · Frailty is a suggested consequence of ageing, but with a variety of different definitions the understanding of what it means to be frail is challenging. There is a common belief that frailty results in a reduction of physical functioning and ability and therefore is likely to significantly affect a person’s quality of life. The aim of this study was to explore the understanding of older ...

  3. 15 de may. de 2024 · Purpose Frailty is common in critically ill patients but the timing and optimal method of frailty ascertainment, trajectory and relationship with care processes remain uncertain. We sought to elucidate the trajectory and care processes of frailty in critically ill patients as measured by the Clinical Frailty Scale (CFS) and Frailty Index (FI). Methods This is a multi-centre prospective cohort ...

  4. 15 de may. de 2024 · Older persons' experiences of frailty were synthesised with reference to three themes: (i) living with frailty: a multidimensional experience; (ii) living with frailty: acceptability and associations; and (iii) living with frailty: resisting and adapting and losing control.

  5. 5 de may. de 2024 · Frailty, as a ‘multidimensional syndrome characterised by decreased reserve and diminished resistance to stressors’ , is associated with increased healthcare utilisation , reduced quality of life and life expectancy . It affects 12% of those over 65 and at least 50% of those over 85 .

  6. Hace 3 días · Background: Changes in skeletal muscle (SKM) with aging are characterized, in part, by reduced SKM strength and altered gene expression, both of which contribute to increased frailty. The age-related accumulation of excess senescent cells promotes the sequela of SKM aging and contributes to increased frailty. Thus, reducing senescent cell burden represents a promising therapeutic approach to ...

  7. 15 de may. de 2024 · Frailty is known to complicate type 2 diabetes. However, frailty in people with type 1 diabetes has not been extensively researched. This review summarises the available evidence on frailty in those with type 1 diabetes.

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